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A cell-permeable compound that blocks the growth and viability of a variety of cancer cell lines (GI50 = 160 nM in NCI-60 cells), but does not affect normal cells.
A cell-permeable, brain permeant, potent, reversible, ATP competitive inhibitor of Cdk4 and Cdk6 (IC50 = 11, 9, and 15 nM for Cdk4/D1, Cdk4/D3 and Cdk6/D2, respectively).
A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC50 = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).
Thermo Scientific™ CaptureSelect™ GoPure™ FcXP 96-well screening plates contain CaptureSelect FcXP Affinity Matrix and provide a versatile platform for sample preparation, handling, and analysis.
Thermo Scientific™ GoPure™ MabCaptureC™ 96-well screening plates contain MabCaptureC Affinity Matrix and provide a versatile platform for sample preparation, handling, and analysis.
Thermo Scientific™ POROS™ Benzyl Hydrophobic Interaction Chromatography (HIC) Resin is a bioprocess high-performance resin engineered for improved impurity removal during large-scale downstream purification of biomolecules.
The Magnetic Stand-96 is designed for paramagnetic bead precipitation from standard 96-well, U-bottom microplates and 0.2 mL PCR plates with no additional accessories.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Formulation
C14H16N4, HCl
Concentration
2.5 mg/mL
For Use With (Application)
This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979)
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC50 = 2.1 nM for human TRPV4).